Mounjaro vs Zepbound: What's the Difference?
Both are tirzepatide, approved for different things. Here is the honest difference.
The short answer
Mounjaro and Zepbound are both tirzepatide, made by Eli Lilly. Mounjaro is FDA-approved to treat type 2 diabetes. Zepbound is FDA-approved for chronic weight management and for obstructive sleep apnea in adults with obesity. Same molecule, different approved uses.
How tirzepatide differs from semaglutide
Tirzepatide acts on two appetite-hormone pathways (GIP and GLP-1); semaglutide acts on one (GLP-1). In trials of the brand drugs, tirzepatide produced larger average weight loss.
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$199 Skeptics’ Trial, see if it works for you
One month of medical-grade compounded semaglutide, the $119 doctor review, and a free B-12/lipotropic injection. No long-term commitment.
Start the 30-day trialWhat the evidence shows
In SURMOUNT-1 (Jastreboff et al., NEJM 2022; PMID 35658024), adults on tirzepatide 15 mg lost an average of about 20.9% of body weight at 72 weeks versus 3.1% on placebo. That studied the brand medication; individual results vary.
How this relates to what we offer
New Hope Weight Loss does not dispense Mounjaro or Zepbound. We provide physician-supervised compounded tirzepatide, which uses the same active ingredient but is not FDA-approved, not brand-identical, and not reviewed by the FDA. A $119 review decides whether it is appropriate for you.
What you can start today at New Hope Weight Loss
After a one-time $119 medical review with Dr. Sharma, eligible patients begin a physician-supervised program with compounded semaglutide from $166 a month or compounded tirzepatide from $233 a month, with a $199 one-month Skeptics' Trial. Compounded semaglutide and tirzepatide are prepared by licensed U.S. pharmacies and are not FDA-approved, not brand-identical, and not reviewed by the FDA for safety, effectiveness, or quality. Care is in person in Orange County and by telehealth across California and additional states.
Frequently asked questions
Are Mounjaro and Zepbound the same?
Both are tirzepatide from Eli Lilly. Mounjaro is FDA-approved for type 2 diabetes; Zepbound for weight management and obstructive sleep apnea in adults with obesity. Same molecule, different approved uses.
Is tirzepatide stronger than semaglutide?
In trials of the brand drugs, tirzepatide produced larger average weight loss (up to about 20.9% in SURMOUNT-1) than semaglutide (about 14.9% in STEP 1). It works on two hormone pathways instead of one. The best choice still depends on your situation.
Is compounded tirzepatide the same as Zepbound or Mounjaro?
No. It uses the same active ingredient but is not FDA-approved, not brand-identical, and not reviewed by the FDA. We never claim it is the brand.
Does Zepbound help with sleep apnea?
Zepbound is FDA-approved for obstructive sleep apnea in adults with obesity, based on the SURMOUNT-OSA trial. That indication applies to the brand product.
Does New Hope Weight Loss offer Mounjaro or Zepbound?
We do not dispense the brand products. We offer physician-supervised compounded tirzepatide from $233/mo after a $119 review, with honest framing about what compounded means.
This article is informational only and not medical advice. Speak with a licensed physician before starting or changing any GLP-1 therapy. Individual results vary. New Hope Weight Loss is a physician-supervised medical weight loss clinic in Costa Mesa, CA. Eligibility for treatment is determined during the medical consultation. Compounded semaglutide and compounded tirzepatide are not the same products as Wegovy®, Ozempic®, Mounjaro®, or Zepbound®.