Ozempic vs Mounjaro: What's the Difference?
Both are diabetes medications used for weight, but different drugs. The honest comparison.
The short answer
Ozempic is semaglutide and Mounjaro is tirzepatide. Both are FDA-approved to treat type 2 diabetes (not for weight loss specifically), and both reduce appetite, so both are sometimes used off-label for weight. Mounjaro works on two hormone pathways; Ozempic on one.
For weight loss
The weight-loss-approved versions are Wegovy (semaglutide) and Zepbound (tirzepatide). In trials of the weight-loss doses, tirzepatide produced larger average loss (about 20.9% in SURMOUNT-1, PMID 35658024) than semaglutide (about 14.9% in STEP 1, PMID 33567185).
Ready to start?
$199 Skeptics’ Trial, see if it works for you
One month of medical-grade compounded semaglutide, the $119 doctor review, and a free B-12/lipotropic injection. No long-term commitment.
Start the 30-day trialHow this relates to what we offer
We do not dispense Ozempic or Mounjaro. We offer physician-supervised compounded semaglutide and tirzepatide, which use the same active ingredients but are not FDA-approved or brand-identical.
What you can start today at New Hope Weight Loss
After a one-time $119 medical review with Dr. Sharma, eligible patients begin physician-supervised compounded semaglutide from $166 a month or compounded tirzepatide from $233 a month, with a $199 one-month Skeptics' Trial. Compounded semaglutide and tirzepatide are prepared by licensed U.S. pharmacies and are not FDA-approved, not brand-identical, and not reviewed by the FDA for safety, effectiveness, or quality. In person in Orange County and by telehealth across California and additional states.
Frequently asked questions
Are Ozempic and Mounjaro the same?
No. Ozempic is semaglutide; Mounjaro is tirzepatide. Both are FDA-approved for type 2 diabetes and both reduce appetite, but they are different molecules.
Which is better for weight loss?
The weight-approved versions are Wegovy and Zepbound. Tirzepatide produced larger average loss in trials. The right choice depends on your situation and is a physician decision.
Can you use Ozempic or Mounjaro for weight loss?
They are diabetes drugs sometimes used off-label by prescription. The on-label weight versions are Wegovy and Zepbound.
Is compounded the same as Ozempic or Mounjaro?
No. Compounded semaglutide and tirzepatide use the same active ingredient but are not FDA-approved or brand-identical. We never claim they are the brand.
What does New Hope offer?
Physician-supervised compounded semaglutide ($166/mo) or tirzepatide ($233/mo) after a $119 review, with honest framing.
This article is informational only and not medical advice. Speak with a licensed physician before starting or changing any GLP-1 therapy. Individual results vary. New Hope Weight Loss is a physician-supervised medical weight loss clinic in Costa Mesa, CA. Eligibility for treatment is determined during the medical consultation. Compounded semaglutide and compounded tirzepatide are not the same products as Wegovy®, Ozempic®, Mounjaro®, or Zepbound®.