How to Store Semaglutide and Tirzepatide Correctly
Most GLP-1s are refrigerated, with some room-temperature flexibility. The honest, practical rules.
The short answer
GLP-1 medications are generally kept refrigerated (about 36 to 46 F), protected from light, and not frozen. Many products allow a limited period at room temperature once in use, but the exact rules depend on your specific product, so follow the instructions your pharmacy and provider give you.
Practical rules
- Refrigerate until first use; do not freeze (freezing can ruin it, do not use it if frozen).
- Keep it in its packaging, away from light and the freezer wall.
- Traveling? use an insulated bag with a cool pack; do not let it freeze or overheat. Carry it in your hand luggage, not a hot car or checked bag.
- Follow the discard date after first use or once left out per your product's limit.
If in doubt
Ask your pharmacy or provider about your specific product's storage and in-use limits. This is general education, not product-specific instructions.
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Frequently asked questions
Does semaglutide need to be refrigerated?
Generally yes, until first use (about 36 to 46 F), protected from light and never frozen. Many products allow a limited time at room temperature once in use; follow your product's instructions.
Can semaglutide be left out of the fridge?
Many products allow a limited period at room temperature once in use, but the exact limit depends on the product. Check your specific instructions and discard after the stated time.
What if my semaglutide froze?
Do not use medication that has frozen; freezing can damage it. Contact your pharmacy or provider.
How do I travel with it?
Use an insulated bag with a cool pack, keep it in hand luggage, and avoid freezing or overheating (no hot cars or checked bags).
Where does New Hope ship from?
Compounded medication ships from the licensed compounding pharmacy in temperature-appropriate packaging. Compounded medications are not FDA-approved.
This article is informational only and not medical advice. Speak with a licensed physician before starting or changing any GLP-1 therapy. Individual results vary. New Hope Weight Loss is a physician-supervised medical weight loss clinic in Costa Mesa, CA. Eligibility for treatment is determined during the medical consultation. Compounded semaglutide and compounded tirzepatide are not the same products as Wegovy®, Ozempic®, Mounjaro®, or Zepbound®.