Semaglutide Injection Sites: Where and How to Inject
The three usual sites, how to rotate, and tips for a comfortable injection. General guidance.
The three usual sites
Subcutaneous GLP-1 injections typically go into the abdomen (about two inches from the navel), the front of the thigh, or the back of the upper arm. Your provider will confirm what is right for you and demonstrate it.
Rotate your sites
Pick a different spot each week to avoid soreness or lumps. Many people rotate around the abdomen, or alternate abdomen, thigh, and arm. Stay about an inch away from the last spot.
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Start the 30-day trialComfortable injection tips
- Clean the skin and let it dry. Pinch a fold of skin if advised.
- Inject at the angle your provider showed you; press and hold, then release.
- Mild redness or a small bump can be normal; rotate sites and tell your provider about persistent reactions.
This is general education. Your clinician teaches you the exact technique for your medication and shows you live at your first visit.
What you can start today at New Hope Weight Loss
After a one-time $119 medical review with Dr. Sharma, eligible patients begin physician-supervised compounded semaglutide from $166 a month or compounded tirzepatide from $233 a month, with a $199 one-month Skeptics' Trial. Compounded semaglutide and tirzepatide are prepared by licensed U.S. pharmacies and are not FDA-approved, not brand-identical, and not reviewed by the FDA for safety, effectiveness, or quality. In person in Orange County and by telehealth across California and additional states.
Frequently asked questions
Where do you inject semaglutide?
Into the fatty layer under the skin, usually the abdomen (about two inches from the navel), front of the thigh, or back of the upper arm. Your provider confirms and demonstrates.
Do I need to rotate injection sites?
Yes, pick a different spot each week to avoid soreness and lumps, staying about an inch from the last spot.
Does the injection hurt?
Most people find it a quick, minor pinch with a small needle. Clean, dry skin and a relaxed site help.
Is a small bump or redness normal?
A little redness or a small bump can be normal. Rotate sites and tell your provider about persistent or worsening reactions.
Does New Hope teach injection technique?
Yes, your provider teaches the exact technique live at your first visit. Compounded medications are not FDA-approved.
This article is informational only and not medical advice. Speak with a licensed physician before starting or changing any GLP-1 therapy. Individual results vary. New Hope Weight Loss is a physician-supervised medical weight loss clinic in Costa Mesa, CA. Eligibility for treatment is determined during the medical consultation. Compounded semaglutide and compounded tirzepatide are not the same products as Wegovy®, Ozempic®, Mounjaro®, or Zepbound®.